Barry Weiss is a hot shot broker – smart, tough, and arrogant! When Barry needs a new heart, he descends into a comically callous world of medically inept doctors and their hard-bitten nurses. Shortly after receiving a heart transplant, Barry finds that everything feels radically wrong, including feelings of kindness and compassion. In effort to find out why, he tracks down the widow of his heart donor and begins a journey of discovery into the real meaning of his new heart.